Task engagement and pupillometry
Task engagement is primarily measured via pupil diameter in humans. Noradrenaline, originating in the locus coeruleus, is thought to mediate task engagement, while dopamine mediates
- But there’s contradictory evidence regarding dominant neuromodulators — NA has long been considered the dominant, but we know that serotonin modulates pupil diameter via both LC and DR interactions, and mu-opioid agonism does as well (opiates/opioids)