Psychedelics enhance small-world propensity
202309151638
LSD induces an increase in small-world propensity functional brain networks (Luppi2021)
- Increase only observed during primarily segregated substate (and for time-averaged FC) when considering binary networks comprising only the strongest connections
- When weight of connections was considered, increased small-world propensity was seen during both substates
- Increase in small-world propensity results from opposing trends (deviation of characteristic path length from random network increased under LSD, reducing propensity; compensated by decrease in deviation of network’s clustering coefficient from a regular network)
- Recapitulates Viol2017
Related & References
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