5-HT
- Stimulation of 5-HT receptors increases excitation in the host cell by reducing outward potassium currents (Andrade2011)
- Preferentially couple to G (GalphaQ11), which activates phospholipase C
- 5-HT receptors are most densely expressed in the cortex, particularly the association cortex and on layer V Pyramidal neurons (Weber2010)