Psychedelic suppress anticorrelations between brain regions
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LSD (Carhart-Harris2016, Carhart-Harris2012, Roseman2014, Tagliazucchi2016, Tagliazucchi2014)
- Contradicts the claim that a psychedelic state should occupy the opposite end of a continuum as loss of consciousness (Luppi2021, Carhart-Harris2014)
- LSD reduces proportion of negative edges across the brain when considering time-averaged FC (Luppi2021)
- No effect of LSD on prevalence of negative edges during primarily integrated substate, significant reduction in primarily segregated substate (Luppi2021)
- Opposite effect as loss of consciousness (Loss of consciousness suppresses anticorrelations between brain regions)
- No effect of LSD on prevalence of negative edges during primarily integrated substate, significant reduction in primarily segregated substate (Luppi2021)
Related & References
Loss of consciousness suppresses anticorrelations between brain regions
anticorrelations are not uniform in time