Positron Emission Tomography
202212171651
Status:
Tags: Neuroimaging
Uses radioactive beta decay (positron emitting radionuclide attached to a biologically active molecule) to image the emissions from a radiolabelled tracer by taking advantage of gamma emissions during the beta decay process.
The scanner detects pairs of gamma rays emitted to construct a 3D image.
Because you are measuring two gamma rays instead of one, you get better resolution than with SPECT.
Common Tracers
- Flurodeoxyglucose (FDG-PET) is a marker for uptake of glucose
- Florbetapir F18 (18F-AV-45 PET) is a marker for beta amyloid accumulation
- [11c]PBB3 Tau is a marker for Tau accumulation
References
BBI Positron Emission Tomography
Fundamental Neuroscience for Neuroimaging