Nobiletin
Summary
200mg with breakfast daily
Will help reset circadian rhythm, improve sleep quality
Stabilize cognitive energy levels
Reduce fat (and some muscle), suppress appetite
Improve breathing
Enhanced stimulation from caffeine
Increased or decreased libido
pharmacology
Interacts with AMPA receptors
Support circadian rhythm
Inhibits CYP1A2 (which metabolizes caffeine)
Stimulates AMPK (lower appetite)
Inhibits NO production
- resets circadian rhythm
- may affect libido (either way)
- stimulating
O-methylated flavone found in citrus peels like from Citrus aurantium. Extensive use in TCM (support metabolic function, promote wellbeing, promote cognitive function).