Psychedelics decrease the integrity of brain networks

202308261709

Previous work has shown that Psychedelics decrease brain network integrity, especially within the default mode network (Carhart-Harris2016a, Johnson2019, Muller2018, Roseman2014). Integrity of functional connectivity is decreased within resting state networks but is increased between normally distinct RSNs.

This can be equally interpreted as representing increased global integration (Tagliazucchi2016, Petri2014) and decreased global-segregation (dosSantos2016).

Reproduced from Carhart-Harris2019a, which reproduced that from Petri2014

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Related Notes

psychedelics disrupt information processing in CSTC loops
Psychedelics suppress the default mode network
Psychedelics increase BOLD signal variance in medial temporal lobes